Loren has died from the "ball light" and have recruited a brute of their own but more intelligent and has a Russian accent named Oleg. The mayor is about to cut the ribbon on live TV between Stillwater and Steelport when a new threat arrives, forcing The Saints to flee by cars but Killbane is one step ahead of them. He ordered his boys to use the rockets and nearly all the cars fell over into the sea. The Saints floating on the water is told by Oleg that it's Killbane who attacked on the bridge and is told there is more people willing to help as The Saints is forced to retreat to Steelport. On the other hand, the mayor, who is a woman goes back to Stillwater, demands a meeting, declaring war on Steelport.
Return to Steelport[edit]
This should be the first time you drive an electric boat. Once you and Pierce and Shaundi is on the boat, follow the GPS to a larger boat. If you want it short, get close to the cabin as you can before freeing Kenzi who's tied up inside the boat. Next is freeing Zimo. Follow the GPS to reach a mansion. Once inside, go to the target and interrogate the first person in any room. Do the same on the top floor followed by the furthest left corner where there's a door and two Morning Star gunmen were inside. Interrogate one more person then shoot and follow the corridors downstairs with the blue target until you reach him.
The next sequence is like the ancient Roman times but it's men carrying the chariot rickshaws. Just shoot all three behind you to end the sequence. Next, follow the GPS via car to Angel's place. Clear out the Luchadors and go inside. Help clear Luchadors coming in, including a brute with a minigun and two more brutes with a flamethrower. After the cutscene, you're free to do Zimo's missions, Kinzie's missions and Angel's missions. The next couple of missions will have names, indicating who you're helping in order for the story to progress.
Snatch (Zimo)[edit]
This one is simple. Follow the GPS, save the girls, call the girls and bring them back to Zimo's place. If you're playing this on medium and hard, watch out because the girls would be in the cars as well and it's up to you to save and recruit them.
Trafficking (Zimo)[edit]
This one is the same with Pierce. Protect Zimo while he make deals with important people throughout the map. Watch out for twists and turns like a police scam or the person runs away because he or she didn't pay. Also on medium and hard as an activity.
Escort (Zimo)[edit]
This one is sort of straight forward. You have to drive around as the red meter goes up. If the blue meter goes up like vans coming after you, avoid them. You need to do at least two things before returning the person to his place. It's also available on medium and hard difficulty.
Trojan Whores[edit]
It's not exactly the same as bringing a giant wooden horse in the Middle Ages. Anyway, a phone call and Shaundi's not happy. At the penthouse, after Shaundi left, one of the girls is about to attack and you stopped it from happening. Then the girls came out with guns, turning a party into a girls with guns war. Well, you start by shooting the girls and be ready to revive Pierce on the top floor, inside the building. Later, you have to snipe more girls on the roof. There would be many so make sure you upgrade bullet damage to lessen the pain. Lastly, use the "annihilator" aka the missile launcher on some helicopters to end the girl party sequence. In the cutscene, Killbane is so angry, he killed Kiki with his hands, leaving Viola feeling sad for the loss of her sister. It will be a few more missions until you'll be able to join up with Viola, defecting from Morning Star and helping you until near the end of the story mode.
Pimps up, Ho's Down[edit]
For a brief cutscene, it shows the mayor, using her speech about laying down the law which you'll see real soon. Zimo will put you in his van. The next part can be really troubling to deal with. First, you're naked and second, whatever you're taking, can make your aiming difficult. Pistols should be recommended in taking accurate shots without using the zoom in as your ADS won't work at all. If you got kids around, be thankful that the nude parts will always be covered up.
Take care of the first few gunmen before unlocking the doors. Take care of the snipers on the top floor before shooting down gunmen and women. As for locations, go to the far corner left and go down, following the blue target. Free the prisoners and clean up the gunmen and women in the underground. The last room involves a brute with a minigun. Take him down to end the mission.
Angel's Training[edit]
Assuming you're following the normal order from your phone you'll get sidetracked by a few missions. All involves easy, medium and hard versions and not all is that easy. Here's a short briefing of each Angel's mission.
Insurance Fraud[edit]
Don't be fooled by the title. All you have to do is pratfall in front of vehicles. Start by doing that to fill in the adrenaline. Then use your adrenaline and sprint to increase floating above the vehicles like you're in the moon. Stop once you reach the target.
Trail Blaze[edit]
This one involves using a fire vehicle to cross multiple checkpoints. The fire in the back will allow you additional seconds when you get close to cars, trucks and pedestrians. Start again if you run out of time.
Eye Of The Tiger[edit]
Of course it's the famous song from the movies but that's not the point. You have to drive a car with a tiger next to you! It's worth less the trouble if you go on the train rails as the tiger will occasionally annoy you, pushing your car slightly aside. Not only that, animal control vans come after you and if your tiger's rage is filled up, your only choice is to do a power slide. If you fill the top bar up, you finished your mission.
Face Your Fear[edit]
Go back to Angel's gym. It's just a chat but at least you fulfil your training.
Ho Boat[edit]
You start with Zimo on the waterboat. Go to the cruise ship directly in front of you. Go on it and save those girls! Open each container for grenades, guns and at least four groups of girls but watch out for the brutes! If your playing casual, take out the brute and later on, a brute with the minigun. Once you opened all containers marked with the yellow target, go to the minigun with the blue target for the next sequence.
You have to clear out boats, gunmen and women, and most importantly, helicopters so Pierce can help bring the girls back to land. If your minigun runs out, find another one close to where you first got in. Once it's cleared twice, go to the helicopter with the blue marker. The final sequence involves using missiles with a homing device. Take care of not just the boats but also jeeps and helicopters and you'll reach land near the end. Choose left to get money from Morning Star or go right to increase income from Zimos.
Gang Bang[edit]
The cutscene shows you, Oleg and Viola meeting for the first time as Viola wants to ally with you but it's hard to turn her down as the army STAG crashes the party, forcing your group to go to the hooker building. Plus you'll meet Kia and later Cyprus Temple at the end of the mission. Not only that, the STAG army has laser guns. Laser guns?! You can shoot them indoors but you'll want to save ammo for going up on the roof.
On the roof, if you want to cut the gun fight down, make sure you refill your ammo on all guns and explosives as using missiles will make short work of the flying laser planes. Not only that, take care of snipers unless you beat the transport planes to it. Revive Oleg after the plane attack before signifying that he'll take one of the planes down. Go down with Viola and take care of the remaining STAG soldiers. You'll reach a police car so use it to drive away from them into Saints HQ via GPS. Go there to end the mission.
This isn't great! Now STAG will be patrolling around Steelport until the end of the story, with the exception of the army base so this is far from over. So much for a breather.